Insitro Machine Learning Biology
Insitro yana haɗa manyan bayanan kwayoyin halittar ɗan adam da bayanan salula tare da koyon injin don nemo ingantattun maƙasudin magunguna da majiyyata da yuwuwar amsawa.
Dubawa
It matters because it tackles the biggest reason drugs fail — picking the wrong target — by grounding discovery in real human biology.
Zurfafa nutsewa
An kafa shi a cikin 2018 ta masanin ilimin lissafi kuma tsohon shugaban Stanford da Coursera Daphne Koller, Insitro ya gina kansa a matsayin kamfanin gano magunguna na 'na'ura-farko'. Babban ra'ayinsa shine samar da manyan bayanai, ginanniyar maƙasudi a cikin gida - ta amfani da samfuran cututtukan da aka samo asali na ɗan adam ('in vitro'), hoto mai girma, da ma'aunin omic - kuma a haɗa su da ɗimbin ƙwayoyin halittar ɗan adam da ƙungiyoyin asibiti kamar UK Biobank. Koyon na'ura sannan ya danganta sa hannu na kwayoyin halitta da na salula zuwa cuta, yana taimakawa gano makasudin da kwayoyin halitta ke nuna suna haifar da rashin lafiya da gaske, da kuma sanya majiyyata cikin rukunoni. Sunan da kansa ya haɗu 'a cikin silico' (ƙididdigewa) da 'in vitro' (biology na lab). Insitro ya yi haɗin gwiwa tare da Gileyad da Bristol Myers Squibb kuma yana mai da hankali kan yankuna kamar na rayuwa, hanta, da cututtukan neurodegenerative.
Fahimtar Fasaha
Hanyar Insitro ta sa hannu tana amfani da koyo na inji akan hotunan likita - alal misali, ƙirar ƙira mai zurfi da ke karanta hanta MRI ko histopathology - don samun nau'ikan nau'ikan ilimin injina.' Gudanar da nazarin haɗin gwiwar genome-fadi akan waɗannan halayen AI da aka samu a cikin yawan adadin bankin halittu na iya bayyana bambance-bambancen kwayoyin halitta, don haka maƙasudin maƙasudi, waɗanda ƙayyadaddun alamun asibiti suka ɓace. Wannan ma'auratan sun haɗu da kwayoyin halittar ɗan adam, mafi ƙarfi shaida cewa abin da ake nufi yana da mahimmanci, tare da ƙuduri mai ƙarfi na phenotypic daga AI.
Dabarun Tasiri
Dabarun mai siyarwa
Taswirorin hanyoyin tallace-tallace suna yin tasiri ga abubuwan da ƙungiyar ku za ta iya ginawa na gaba.
Kudin da kasafin kuɗi
Sharuɗɗan kasuwanci da zaɓuɓɓukan turawa suna shafar farashi da haɗari na dogon lokaci.
Haɗari da aminci
Ƙwararrun kamfani suna siffanta ɓangarorin samfur, yanayin aminci, da buɗewa.
Makomar Insitro Machine Learning Biology
Insitro yana turawa zuwa ƙirar tsinkaya waɗanda ke haɗa genotype zuwa salon salula zuwa sakamakon haƙuri, yana ba da damar zaɓin manufa da rarrabuwar haƙuri kafin gwaji masu tsada. Yi tsammanin zurfafa amfani da samfuran tushe a cikin hoto da omics, ƙarin haɗin gwiwar bankin halittu, da haɓaka ƴan takarar bututun ciki. Babban ƙalubalen shine rufe madauki: tabbatar da cewa AI-wanda aka zaɓa, makasudin tallafawa kwayoyin halitta suna fassara zuwa magungunan da aka yarda da su waɗanda ke aiki a cikin majinyata masu dacewa.
Aiwatar da Gaskiyar Duniya
Samfuran horarwa akan hanta MRI na sikanin don ƙirƙirar ƙididdiga masu ƙima, sannan gudanar da nazarin ƙungiyar kwayoyin halitta don nemo maƙasudin miyagun ƙwayoyi don cutar hanta.
Yin amfani da ƙananan ƙwayoyin da aka samo asali na ɗan adam don ƙirar ALS da sauran cututtukan neurodegenerative don nazarin ML.
Haɗin kai tare da Gileyad don gano maƙasudin steatohepatitis (NASH) da fibrosis na hanta.
Ƙirƙirar majiyyata zuwa ƙungiyoyin ƙayyadaddun kwayoyin halitta don hasashen wanda zai amsa maganin da aka ba shi.
Hatsari & Tsare-tsare
Sanarwar ƙaddamarwa na iya ƙetare kwanciyar hankali a cikin ayyukan samarwa na gaske.
Farashin API ko sauye-sauyen manufofi na iya karya zato cikin dare.
Dogaro mai siyarwa guda ɗaya yana ƙara kulle-kulle da farashin ƙaura.
Taswirar Hanya
Kimanta masu samarwa ta amfani da ayyukan ku da saitin bayanai.
Yi bitar sirri, tsaro, da sharuɗɗan doka kafin haɗin kai.
Kula da tsarin koma baya a cikin samfura ko masu siyarwa.
Saka idanu bayanin kula don haka canje-canjen taswirar hanya kada suyi mamakin ƙungiyoyi.
Ci gaba da Bincike
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Jagora na gaba
Tushen Koyon Inji
Tambayoyin da ake yawan yi
What is Insitro Machine Learning Biology?
Insitro yana haɗa manyan bayanan kwayoyin halittar ɗan adam da bayanan salula tare da koyon injin don nemo ingantattun maƙasudin magunguna da majiyyata da yuwuwar amsawa. Yana da mahimmanci saboda yana magance babban dalilin da yasa kwayoyi ke kasa - ɗaukar manufa mara kyau - ta hanyar gano ainihin ilimin halittar ɗan adam.
Menene sunan 'Insitro' ya haɗu?
Sunan ya haɗu 'a cikin lissafin silico' tare da 'in vitro' ilmin halitta na lab, yana ɗaukar tsarin gwaji na ML-plus.
Wanene ya kafa Insitro?
Daphne Koller, masanin ilimin lissafi kuma tsohon wanda ya kafa Coursera, ya kafa Insitro a cikin 2018.
Me yasa Insitro ya jaddada jinsin ɗan adam a cikin zaɓin manufa?
Manufofin da suka goyi bayan shaidar kwayoyin halittar ɗan adam sun fi dacewa su zama sanadi na gaske, suna rage gazawar ƙwayoyi.
Menene 'phenotype na koyon inji' kamar yadda Insitro ke amfani da shi?
Insitro yana samun halaye masu ƙididdigewa daga hotuna ta amfani da ML, sannan yayi nazarin ƙungiyoyin jinsin su.
Wace babbar ƙungiyar ɗan adam ce aka fi amfani da ita don nazarin sikelin kwayoyin halitta kamar na Insitro?
Bankin Biobank na Burtaniya ya haɗu da kwayoyin halitta, hoto, da bayanan kiwon lafiya ga dubban ɗaruruwan mutane.