Incamake
Insitro ihuza amakuru manini yumuntu hamwe na selile yiga imashini kugirango ibone intego nziza zibiyobyabwenge nabarwayi bashobora kwitabira. Nibyingenzi kuko ikemura impamvu ikomeye ibiyobyabwenge binanirwa - guhitamo intego itari yo - hashingiwe kubuvumbuzi bwibinyabuzima nyabyo byabantu.
Insitro Imashini Yiga Ibinyabuzima byumvikana neza murwego rwingamba, kugera kubitegererezo, ibyemezo bya platform, hamwe nubufatanye bwibidukikije.
Kwibira cyane
Insitro yashinzwe mu mwaka wa 2018 n’umuhanga mu binyabuzima w’ibinyabuzima ndetse n’uwahoze ari umuyobozi wa Stanford n’umuyobozi wa Coursera, Daphne Koller, Insitro yubatse nka sosiyete yiga ibiyobyabwenge 'imashini yiga-mbere'. Igitekerezo cyacyo nyamukuru ni ugukora imibare nini, yubatswe nintego murugo - ukoresheje ingero zindwara zikomoka ku bantu ('muri vitro'), kwerekana amashusho menshi, hamwe n 'ibipimo bya omics - no kubihuza n’ingingo nini z’abantu n’ubuvuzi nka Biobank yo mu Bwongereza. Kwiga imashini noneho bihuza umukono wa molekuline na selile nindwara, bifasha kumenya intego genetiki yerekana ko itera uburwayi, kandi igabanya abarwayi mumatsinda mato. Izina ubwaryo rihuza 'muri silico' (kubara) na 'muri vitro' (biologiya ya laboratoire). Insitro yafatanije na Galeedi na Bristol Myers Squibb kandi yibanda ku bice nka metabolike, umwijima, n'indwara zifata ubwonko.
Ubushishozi
Umukono Insitro ikoresha imashini yiga imashini kumashusho yubuvuzi - urugero, moderi yimbitse isoma umwijima MRI cyangwa histopathology - kugirango ibone 'fenotipike yiga imashini.' Gukoresha genome-ishyirahamwe ryiga kurwanya iyo mico ikomoka kuri AI mubantu bangana na biobank irashobora kugaragara kubinyabuzima bitandukanye, bityo rero intego zitera, ibyo birango byamavuriro bikabura. Ibi bihuza genetiki yabantu, ibimenyetso bikomeye byerekana ko intego ifite akamaro, hamwe na fenotipiki ikungahaye kuri AI.
Kumenya Imashini ya Insitro Kwiga Biologiya
Insitro ihuza amakuru manini yumuntu hamwe na selile yiga imashini kugirango ibone intego nziza zibiyobyabwenge nabarwayi bashobora kwitabira. Nibyingenzi kuko ikemura impamvu ikomeye ibiyobyabwenge binanirwa - guhitamo intego itari yo - hashingiwe kubuvumbuzi bwibinyabuzima nyabyo byabantu. Insitro Imashini Yiga Ibinyabuzima byumvikana neza murwego rwingamba, kugera kubitegererezo, ibyemezo bya platform, hamwe nubufatanye bwibidukikije. Kugira ngo wubake byimbitse, fata Insitro Machine Learning Biology nk'icyitegererezo gikora, ntabwo ari ikintu kimwe: gusobanura ibyagezweho, gusobanura ibitekerezo, no gutandukanya ibyo sisitemu ishobora gukora byizewe nibisaba guca imanza zinzobere.
Mu myitozo, amatsinda akomeye akoresha Insitro Machine Learning Biology asuzuma ingamba zabacuruzi, ikarita yerekana ikarita yizewe, hamwe ningaruka zo gufunga mbere yo gukora. Bandika ibipimo ngenderwaho byerekana intsinzi, bagerageza kurwanya amakuru afatika hamwe nakazi keza, kandi bagasubiramo bashingiye kubikorwa byagaragaye ko batsinzwe aho gutsinda inshuro imwe. Aha niho imyumvire yubumenyi ihinduka mubushobozi burambye kubicuruzwa, politiki, nibikorwa.
Ibishushanyo mbonera byabacuruzi bigira ingaruka kubiranga ikipe yawe ishobora kubaka ubutaha. Mugihe kimwe, Amatangazo yo gutangiza arashobora gusumbya umutekano mubikorwa nyabyo byakazi. Uburyo bukomeye cyane ni uguhuza umuvuduko wikigereranyo hamwe na disipuline yimiyoborere: kuyobora abaderevu, gufata ibimenyetso, gutangaza ibyemezo byicyemezo, no gukomeza kuvugurura uburyo bwo kwirinda nkimyitwarire yicyitegererezo, ibyo abakoresha bategereje, nibisabwa n'amategeko bigenda bihinduka.
Ingaruka z'Ingamba
Ibishushanyo mbonera byabacuruzi bigira ingaruka kubiranga ikipe yawe ishobora kubaka ubutaha.
Ibishushanyo mbonera byabacuruzi bigira ingaruka kubiranga ikipe yawe ishobora kubaka ubutaha. Mubikorwa byujuje ubuziranenge, ibi bihindurwa mumategeko agenga imikorere, imipaka nyirubwite, hamwe n'imihango yo gusubiramo kenshi kugirango amakipe ashobore kwigirira ikizere aho gupima ibidasobanutse.
Amagambo yubucuruzi nuburyo bwo kohereza bigira ingaruka kubiciro byigihe kirekire ningaruka.
Amagambo yubucuruzi nuburyo bwo kohereza bigira ingaruka kubiciro byigihe kirekire ningaruka. Mubikorwa byujuje ubuziranenge, ibi bihindurwa mumategeko agenga imikorere, imipaka nyirubwite, hamwe n'imihango yo gusubiramo kenshi kugirango amakipe ashobore kwigirira ikizere aho gupima ibidasobanutse.
Isosiyete ishimangira gushiraho ibicuruzwa bitemewe, igihagararo cyumutekano, no gufungura.
Isosiyete ishimangira gushiraho ibicuruzwa bitemewe, igihagararo cyumutekano, no gufungura. Mubikorwa byujuje ubuziranenge, ibi bihindurwa mumategeko agenga imikorere, imipaka nyirubwite, hamwe n'imihango yo gusubiramo kenshi kugirango amakipe ashobore kwigirira ikizere aho gupima ibidasobanutse.
Gushyira mu bikorwa Isi
Uburyo bwo guhugura umwijima MRI isuzuma kugirango habeho fenotipike yuzuye, hanyuma ukore ubushakashatsi bwishyirahamwe ryerekeranye nubuzima kugirango ushakishe ibiyobyabwenge indwara zumwijima.
Gukoresha stem-selile-muntu ikomoka kuri neuron kugirango yerekane ALS nizindi ndwara zifata ubwonko bwa ML.
Gufatanya na Galeedi kuvumbura intego za steatohepatite idafite inzoga (NASH) na fibrosis yumwijima.
Gutandukanya abarwayi mumatsinda mato kugirango bahanure uzitabira imiti yatanzwe.
Uburyo bwo Gushyira mu bikorwa
Insitro Imashini Yiga Ibinyabuzima mubikorwa
Uburyo bwo guhugura umwijima MRI isuzuma kugirango habeho fenotipike yuzuye, hanyuma ukore ubushakashatsi bwishyirahamwe ryerekeranye nubuzima kugirango ushakishe ibiyobyabwenge indwara zumwijima.
Uburyo bwo guhugura umwijima MRI isuzuma kugirango habeho fenotipike yuzuye, hanyuma ukore ubushakashatsi bwishyirahamwe ryerekeranye nubuzima kugirango ushakishe intego yibiyobyabwenge byindwara zumwijima Amakipe akunze kubona umusaruro mwiza mugihe asobanura ibipimo ngenderwaho byimbere, agakomeza inzira yo kuzamuka kwabantu kubibazo byanduye, kandi agakurikirana inyungu zumusaruro hamwe nibiciro byamakosa mugihe runaka.
Insitro Imashini Yiga Ibinyabuzima mubikorwa
Gukoresha stem-selile-muntu ikomoka kuri neuron kugirango yerekane ALS nizindi ndwara zifata ubwonko bwa ML.
Gukoresha neuron-stem-selile ikomoka kuri neuron kugirango yerekane ALS nizindi ndwara zifata ubwonko bwa ML isesengura Amakipe ubusanzwe abona ibisubizo byiza iyo asobanuye ibipimo ngenderwaho byimbere, agakomeza inzira yo kuzamura abantu kubibazo byimbere, kandi agakurikirana inyungu zibyara umusaruro nibiciro byamakosa mugihe.
Insitro Imashini Yiga Ibinyabuzima mubikorwa
Gufatanya na Galeedi kuvumbura intego za steatohepatite idafite inzoga (NASH) na fibrosis yumwijima.
Gufatanya na Galeedi kuvumbura intego ziterwa na steatohepatite idafite inzoga (NASH) hamwe na fibrosis yumwijima Amakipe akunze kubona umusaruro ushimishije mugihe asobanura ibipimo ngenderwaho byimbere, agakomeza inzira yo kuzamuka kwabantu kubibazo bikabije, kandi akurikirana inyungu zibyara umusaruro nibiciro byigihe.
Insitro Imashini Yiga Ibinyabuzima mubikorwa
Gutandukanya abarwayi mumatsinda mato kugirango bahanure uzitabira imiti yatanzwe.
Gutandukanya abarwayi mu matsinda mato kugira ngo bahanure uzitabira imiti yatanzwe Amakipe ubusanzwe abona ibisubizo byiza iyo asobanuye ibipimo ngenderwaho biri imbere, agakomeza inzira yo kuzamura abantu ku manza, kandi akurikirana inyungu zibyara umusaruro hamwe n’ikosa ryigihe.
Ingaruka & Kurinda
Gutangiza amatangazo arashobora gusumbya ituze mubikorwa nyabyo byakazi.
Ibiciro bya API cyangwa guhindura politiki birashobora guhagarika ibitekerezo ijoro ryose.
Abashoramari bonyine bishingira byongera gufunga no kwimuka.
Igishushanyo mbonera
Suzuma abatanga serivisi ukoresheje imirimo yawe bwite na datasets.
Suzuma abatanga serivisi ukoresheje imirimo yawe bwite na datasets. Fata buri ntambwe nk irembo ryibimenyetso: niba ibipimo bitujujwe, hagarika kuzenguruka, funga icyuho, hanyuma noneho wagure imikoreshereze.
Ongera usuzume ubuzima bwite, umutekano, namategeko mbere yo kwishyira hamwe.
Ongera usuzume ubuzima bwite, umutekano, namategeko mbere yo kwishyira hamwe. Fata buri ntambwe nk irembo ryibimenyetso: niba ibipimo bitujujwe, hagarika kuzenguruka, funga icyuho, hanyuma noneho wagure imikoreshereze.
Komeza gahunda yo gusubira inyuma kurugero cyangwa abacuruzi.
Komeza gahunda yo gusubira inyuma kurugero cyangwa abacuruzi. Fata buri ntambwe nk irembo ryibimenyetso: niba ibipimo bitujujwe, hagarika kuzenguruka, funga icyuho, hanyuma noneho wagure imikoreshereze.
Kurikirana inyandiko zisohora kugirango impinduka zumuhanda ntizitangaje amakipe.
Kurikirana inyandiko zisohora kugirango impinduka zumuhanda ntizitangaje amakipe. Fata buri ntambwe nk irembo ryibimenyetso: niba ibipimo bitujujwe, hagarika kuzenguruka, funga icyuho, hanyuma noneho wagure imikoreshereze.