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AlphaFold
AlphaFold i Google DeepMind AI inofanotaura chimiro che 3D chemapuroteni kubva mukutevedzana kwawo kwemaamino-asidhi, dambudziko guru remakore makumi mashanu mubiology.
Teerera kugwaro iriAI-yakarondedzerwa · ~2 min
Pa peji ino2 min verenga
Pfupiso
Its breakthrough earned a share of the 2024 Nobel Prize in Chemistry.
Kudzika Kwakadzika
Mapuroteni maketani emaamino acids anopeta kuita akaomarara e3D zvimiro, uye chimiro ichocho chinotaridza zvinoitwa neprotein, kubva pakutakura okisijeni kuenda kurwisa hutachiona. Kufanotaura kupeta kubva mukutevedzana chete kwakagumbura masayendisiti kwemakumi emakore. Muna 2020, AlphaFold 2 yakakatyamadza nhandare pamakwikwi eCASP14, ichifanotaura zvimiro zvine huchokwadi kukwikwidza zvinononoka, zvinodhura lab nzira seX-ray crystallography. DeepMind yakabva yaburitsa anopfuura mamirioni mazana maviri akafanotaurwa zvimiro, anofukidza anenge ese anozivikanwa mapuroteni, emahara kune vanoongorora. Muna 2024, AlphaFold 3 yakawedzera fungidziro yekuti mapuroteni anodyidzana sei neDNA, RNA, mishonga, uye mamwe mamorekuru. Demis Hassabis naJohn Jumper vakagovera 2024 Nobel Prize muChemistry yebasa racho.
Kuitwa muNyika yeChokwadi
Kupa emahara 3D zvimiro zveanopfuura mamirioni mazana maviri mapuroteni kune vanoongorora pasi rese
Kumhanyisa kuwanikwa kwezvinodhaka nekuburitsa kuti mamorekuru emumiriri anosunga sei puroteni inonangwa
Kubatsira kugadzira ma enzymes matsva, kusanganisira ayo anopwanya marara epurasitiki
Kubatsira kutsvagisa marariya, Parkinson's, uye kurwisa kwemishonga inorwisa mabhakitiriya nekugadzira mepu mapuroteni akakosha
Ramangwana reAlphaFold
AlphaFold iri kukurumidza kuwanikwa kwezvinodhaka, dhizaini ye enzyme, uye kunzwisisa kwezvirwere zvakaita semarariya uye nemishonga inorwisa mabhakitiriya. Nhungamiro dzeramangwana dzinosanganisira kufanotaura mapuroteni ekuchinja uye kufamba, kwete kungotora mifananidzo, kuenzanisira hombe dzemamorekuru, uye kusanganisa kwakasimba nedata rekuyedza. Vhura dhatabhesi uye spin-offs seIsomorphic Labs inovavarira kushandura chimiro chekufungidzira kuita mishonga inokurumidza, isingadhuri. Tarisira AI chimiro kufanotaura kuve nhanho yekutanga nhanho mune dzinenge dzese molecular biology.
Kuzvishandisa
Nei zvichikosha
- Nzira yemutengesi. Mamepu emigwagwa emutengesi anopesvedzera izvo izvo timu yako inogona kugadzira inotevera.
- Mutengo uye bhajeti. Mamiriro ezvekutengeserana uye sarudzo dzekuendesa dzinokanganisa mutengo wenguva refu uye njodzi.
- Ngozi uye kuchengeteka. Kambani inokurudzira inogadzirisa kusarudzika kwechigadzirwa, mamiriro ekuchengetedza, uye kuvhurika.
Chenjera
- Zviziviso zvekutanga zvinogona kupfuura kugadzikana mune chaiyo yekugadzira workflows.
- Mitengo yeAPI kana shanduko yepolicy inogona kukanganisa fungidziro husiku.
- Kutsamira kune mumwe-mutengesi kunowedzera kukiya-mukati uye mari yekufambisa.
Matanho anotevera
- Ongorora vanopa uchishandisa ako ega mabasa uye dataset.
- Wongorora zvakavanzika, chengetedzo, uye mazwi emutemo usati wabatanidzwa.
- Chengetedza chirongwa chekudzokera kumashure kune mamodheru kana vatengesi.
- Tarisa zvinyorwa zvekuburitsa kuitira kuti shanduko yemigwagwa isashamise zvikwata.
Ramba Uchiongorora
Tsamba yemahara
Tora iyo yemazuva ese AI pfupiso
Nhatu dzakasimbiswa dzeAI nyaya mangwanani ega ega pakati pevhiki, dzakanyorwa neChirungu chakajeka. Yemahara zvachose, hapana ads.
Imwe email zuva rega rega revhiki. Bvisa kunyoresa kamwe chete. Hatimbotengese kana kugovera kero yako.
Zviedze iwe pachako
Take the AlphaFold quiz
Mhinduro yepakarepo pamhinduro yega yega, uye chitupa chinogovaniswa chine ID inobatika kana wapedza kosi.
Tsigira dzidzo yemahara yeAI. AI Understanding ndeye 501(c)(3) isingabatsiri - hapana ads, hapana paywall, zvachose. Ita chipo
Mibvunzo inowanzo bvunzwa
What is AlphaFold?
AlphaFold i Google DeepMind AI inofanotaura chimiro che 3D chemapuroteni kubva mukutevedzana kwawo kwemaamino-asidhi, dambudziko guru remakore makumi mashanu mubiology. Kubudirira kwayo kwakawana chikamu che2024 Nobel Prize muChemistry.
AlphaFold inofanotaura chii?
AlphaFold inofanotaura kuti puroteni inopeta sei muchimiro chayo che 3D zvichienderana nekutevedzana kwayo kwemaamino acids.
How can a protein’s 3D structure help researchers study its function?
Structure can guide hypotheses about molecular interactions and possible function, but biological activity still requires context and evidence.
Ndeipi chiitiko che2020 iyo AlphaFold 2 yakaratidza kubudirira kwayo?
AlphaFold 2 yakashamisa masayendisiti pamakwikwi eCASP14 protein-structure-prediction muna 2020.
Ndeipi chiratidzo chekushanduka-shanduka chinoshandiswa neAlphaFold 2 kuwana kuti ndeapi maamino acids ari pedyo nemumwe?
Nekuenzanisa mapuroteni ane hukama mumarudzi ese, AlphaFold inoona inoshanduka-shanduka amino acids iyo inogona kunge iri pedyo pamwe chete mu3D.
Ndekupi kuzivikanwa kukuru kwakagamuchirwa nevagadziri veAlphaFold muna 2024?
Demis Hassabis naJohn Jumper vakagovana 2024 Nobel Prize muChemistry yeAlphaFold.
Ramba uchidzidza
Mazano anoenderana
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