Kwenzekeni
I-Enveda Biosciences, inkampani etholakala e-AI eseColorado, imemezele ukuthi inyuse amaRandi ayizigidi ezingama-311 emzuliswaneni wokuxhasa ngezimali u-Series E. Uxhaso, oluholwa yi-Catalio Capital Management ngokubambisana kwabanye abatshalizimali abangu-16 okuhlanganisa no-T. Rowe Price kanye ne-Lux Capital, luzosetshenziselwa ukuthuthukisa ipayipi lenkampani labantu abazofuna izidakamizwa ezikhonjwe yi-AI. I-Enveda isebenzisa ubuhlakani bokwenziwa ukuze imbe izitshalo namagciwane ezimayini ukuze ithole amangqamuzana, ibikezela ukwakheka nokusebenza kwawo ukuze kulinganiswe amandla ezidakamizwa. Njengamanje, abathathu balaba bantu abaphuma ku-AI bahlolwa abantu: i-ENV-294 ye-atopic dermatitis nesifuba somoya, i-ENV-308 yokulondoloza isisindo ngemva kokwelashwa kwe-GLP-1, kanye ne-ENV-6949 yesifo samathumbu esivuvukalayo.
I-Enveda Biosciences imemezele ngoLwesithathu ukuthi ivale umzuliswano wezimali we-Series E wama- $ 311 wezigidi. Le nkampani, ezinze eColorado, isebenzisa ubuhlakani bokwenziwa ukuhlonza ama-molecule ezinto eziphilayo njengezitshalo namagciwane, ibikezela ukwakheka nokusebenza kwawo ukuze kulinganiswe amandla awo njengabazokhethwa ezidakamizwa.
Umjikelezo woxhaso wawuholwa yiCatalio Capital Management futhi wawuhlanganisa nabanye abasekelayo abangu-16, abafana ne-Surveyor Capital, T. Rowe Price, Lux Capital, kanye nesikhwama somcebo ozimele. Lokhu kuletha isamba sebhizinisi lika-Enveda sisekelwa ngaphezu kwezigidi ezingama- $841, okuhlanganisa nomjikelezo wangaphambilini we-Series D wama- $ 150 wezigidi ngo-2025.
Njengamanje i-Enveda inamakhandidethi amathathu ezidakamizwa asuselwa ku-AI ekuhlolweni kwabantu. I-ENV-294 iphilisi le-'molecular glue' le-atopic dermatitis kanye nesifuba somoya, nokuhlolwa kweSigaba 2 kuyaqhubeka. I-ENV-308 yakhelwe ukulingisa ihomoni i-Lac-Phe ekhishwa ngesikhathi sokuzivocavoca, okuhloswe ngayo ukusiza ukwehlisa isisindo ngemuva kokuyeka izindlela zokwelapha ze-GLP-1. I-ENV-6949 iqonde indlela ye-TL1A yesifo samathumbu esivuvukalayo.
Isikhulu esiphezulu uViswa Colluru sithe inkampani ihlola izinhlelo eziyi-17 eziphuma ocwaningweni lwayo lwe-AI. Isu lenkampani libandakanya ukufaka izidakamizwa eziningi emtholampilo kanye nokubambisana nazo ezindaweni zokuguquguquka kwenani ukuze kuqinisekiswe kokubili ukuqinisekiswa kanye nemali ukuze kuthuthukiswe ezinye izimpahla zamapayipi.
Imininingwane yomthombo: biopharmadive.com ↗
Kungani kubalulekile
Lo mjovo wemali obalulekile uqinisekisa ukusebenza kwezentengiselwano kokutholakala kwezidakamizwa eziqhutshwa yi-AI, ikakhulukazi ekuhlonzeni izindlela ezintsha ezivela emithonjeni yemvelo. Ngokuxhasa ngezimali ukuqhubeka komtholampilo kwesigaba sekwephuzile, i-Enveda ihlose ukukhombisa ukuthi i-AI ingasheshisa ukuthuthukiswa kwezindlela zokwelapha ezisezingeni lokuqala ezimweni eziyinkimbinkimbi njengokukhuluphala kanye nokuphazamiseka komzimba. Usayizi womzuliswano, ophikisana nama-IPO athile e-biotech, ubonisa ukuzethemba okuqinile kwabatshalizimali ekusetshenzisweni okungokoqobo kwe-AI ku-R&D yezemithi, okungase kushintshe amazinga embonini wokuthi abantu abasha bemithi bathola futhi bagunyazwe kanjani.
Ukukhushulwa kwezigidi ezingu-311 zamaRandi kukhulu ku-pre-IPO biotech, isamba esincintisanayo esivikelwe emithonjeni emikhulu yokuqala yomphakathi kulo nyaka. Lokhu kuphakamisa ukuthi abatshalizimali babeka inani eliphezulu ekhonweni le-AI lokususa ubungozi nokusheshisa ukutholwa kwezidakamizwa kusenesikhathi.
Indlela ka-Enveda yokumba imithombo yemvelo yezimayini njengezitshalo namagciwane asebenzisa i-AI imele uguquko oluhlukile lwendlela yokusebenza kusukela ekuhloleni okungokwesiko okuphezulu noma umklamo we-computational de novo. Ukuphumelela kwamakhandidethi ayo amanje emtholampilo kuzoba uvivinyo olubalulekile lwale ndlela yokusebenza ngempumelelo.
Ukugxilwa kokukhuluphala kanye nezifo zokuzivikela komzimba kuqondisa izindawo ezinesidingo esikhulu ezingafinyeleleki ezinamandla amakhulu okuhweba. Ngokucacile, umgomo we-ENV-308 wokulondoloza ukwehla kwesisindo ngemva kokuyekiswa kwe-GLP-1 uqondise igebe elibucayi kuma-paradigms amanje okwelapha ukukhuluphala.
Lolu xhaso luvumela u-Enveda ukuthi athuthuke emtholampilo ngaphandle kwesidingo esiphuthumayo se-IPO, enikeza isikhathi sokukhiqiza idatha yomtholampilo eqine kakhudlwana engase ikhulise ukulinganisa kwayo noma yenze lula ubudlelwano bamasu.
I-Interactive Mechanism: Indlela Esebenza Ngayo Ngempela
Hlola ubuchwepheshe obuyisisekelo ngemuva kwalokhu kuthuthukiswa ngokuhlanganyela.
What did neural scaling law research (e.g. Kaplan et al., 2020) observe?
Ongakubuka ngokulandelayo
Abatshalizimali nababukeli bezimboni kufanele baqaphe imiphumela yesilingo seSigaba 2 se-ENV-294 ku-eczema nesifuba somoya, kanye nokuhlolwa okuzayo kwe-ENV-308 ukuze kusetshenziswe ukugcinwa kwesisindo ngemuva kwe-GLP-1. Ukwengeza, bheka ubambiswano lwamacebo noma amadili okulayisense u-Enveda engase awamemezele ukuze axhase ukuthuthukiswa kwamapayipi, njengoba i-CEO u-Viswa Colluru ebonise isu lozakwethu lwezimpahla ezindaweni zokuguquguquka kwenani ukuze kutholakale imali yezinye izinhlelo.
Imiphumela yohlolo oluqhubekayo lweSigaba 2 se-ENV-294 ku-eczema kanye nesifuba somoya izoba yingqophamlando, njengoba izohlinzeka ngobufakazi obuqinisekile bokusebenza komuthi kanye nephrofayili yokuphepha.
Ukuqaliswa kanye nemiphumela yokuqala yokuhlolwa kwe-ENV-308 ekusetshenzisweni kokugcinwa kwesisindo ngemuva kwe-GLP-1 kuzobhekwa kakhulu, uma kubhekwa intshisekelo yemakethe ephezulu ekwelapheni ukukhuluphala okusimeme.
I-Enveda ingase imemezele amasu obambiswano noma izivumelwano zamalayisense ezimpahleni zayo ezihamba phambili, njengoba kuboniswa isu le-Colluru lokubambisana ezindaweni zokuguquguquka kwenani ukuze kuxhaswe intuthuko eyengeziwe.
Inqubekelaphambili yenkampani ekuthuthukiseni ezinye izinhlelo zayo ezihlolisisiwe eziyi-14 kusukela esigabeni socwaningo lwe-AI kuya ezivivinyweni zomtholampilo izokhombisa ukuqina kwenkundla yayo yokutholwa eqhutshwa yi-AI.