IA ci laaj ak tontu ci genomik

Sooy def quiz bi, tontu yi ak leeral yi dañuy feeñ.

1. Roughly how many base pairs are in one haploid human reference genome?
   • Lu tollu ci 3 milyaar
   • Lu tollu ci 3 junni
   • Lu tollu ci 3 milioŋ
   • Lu tollu ci 3 bilioŋ
2. Lan la AlphaMissense bu DeepMind wax luy waaja am?
   • Njëg li ci terapi genetik
   • Ndax mutation missense yi mën nañu nekk lu baax wala luy indi feebar
   • Deretu malaad bi
   • Formu seluli deret yu xonk yi
3. Lan moo waral xeetu juntuwaay yu bees yi di faral di jappee ADN ni 'lakk'?
   • Ndax ci tubaab lañu ko bind
   • Ndax gene yi mën nañu wax
   • Ndax araf yu gudd lañu (A, C, G, T) ak motif yuñ mëna jàng
   • Ndax dafay jëfandikoo ay tombi ponksioŋ
4. Luy poñ risk polygenic?
   • Test ngir benn gene bu yàqu
   • Natt limu gene yi nga am
   • Njortu ngir gaawaayu toppalante ADN
   • Xayma risku feebar bu boole ay jafe-jafe genetik yu ndaw
5. In AlphaMissense, how does evolutionary conservation function in the model?
   • It is one signal combined with structural context to help predict missense effects
   • It proves every change at a conserved position is harmful
   • It alone determines a clinical diagnosis
   • It measures a patient’s disease severity
6. Lan mooy mébetu IA ci defar CRISPR guide RNAs?
   • Ngir ADN bi leer
   • Ngir yokk coppite yiñ bëgga def ak wàññi jafe-jafe yi nekk ci biti
   • ngir yeexal xaajalug selil
   • Tekki ADN ci protein
7. What information did AlphaMissense use in adapting an AlphaFold-based model for missense-effect prediction?
   • Only a patient’s symptoms
   • Only CT images
   • Human and primate variant population-frequency data
   • A list of medical billing codes
8. How should a predicted pathogenicity score be used in clinical variant interpretation?
   • As a stand-alone diagnosis
   • As proof that a person will develop disease
   • As a replacement for genetic counseling
   • As one computational evidence source alongside clinical and functional evidence