Cuestionario vinculado a una guía · Medio Nivel
Prueba de predicción de IA de lesión renal aguda
Prueba la definición de IRA de KDIGO, lo que realmente hicieron el estudio DeepMind-VA y la aplicación Streams, y por qué las alertas de IRA no han mejorado los resultados de manera confiable.
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Under the KDIGO criteria described in this guide, which creatinine change within 48 hours qualifies as acute kidney injury?
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Las respuestas y explicaciones aparecen a medida que realiza el cuestionario.
- Under the KDIGO criteria described in this guide, which creatinine change within 48 hours qualifies as acute kidney injury?
- A rise of 0.1 mg/dL
- A rise of at least 0.3 mg/dL
- A fall of at least 0.3 mg/dL
- Any value above 1.0 mg/dL
- Why do AKI models try to predict injury instead of waiting for creatinine to rise?
- Creatinine tests are too expensive to repeat
- Creatinine can only be measured in the ICU
- Creatinine is a lagging marker, so the injury may already be a day or more old when it rises
- Creatinine falls during kidney injury
- In the 2019 DeepMind and VA study, roughly how many false alerts came with each correct AKI prediction?
- About two
- About twenty
- Ninguno
- About one false alert per hundred true ones
- Which group did the VA-trained AKI model perform worse for, and why?
- Older patients, because they have less lab data
- Women, because they were a small share of the VA training population
- ICU patients, because their creatinine is measured too often
- Surgical patients, because anesthesia hides creatinine changes
- What did DeepMind's Streams app at the Royal Free Hospital actually deliver to clinicians?
- Deep learning predictions of AKI 48 hours ahead
- Automated dialysis orders
- Genetic risk scores for kidney disease
- Alerts from the rule-based NHS England AKI algorithm
- What did the Yale randomized trials of electronic AKI alerts find?
- Alerts halved the need for dialysis
- Alerts did not improve outcomes such as dialysis or death overall
- Alerts only worked when sent by text message
- Alerts made creatinine measurements more accurate
- Why does the guide call missing lab data 'informative' in AKI models?
- Missing values are always errors in the database
- Labs are missing only for patients who died
- A lab that was never ordered often means the clinician wasn't worried, so the ordering pattern itself predicts risk
- Missing values are filled in by the laboratory later
- Why should an AKI model's evaluation exclude patients who already meet AKI criteria when the prediction is made?
- To avoid giving the model credit for spotting injuries that are already known
- Because those patients have no creatinine data
- Because the law forbids scoring them
- Because they always go on to need dialysis