Questionário sobre IA em segurança de medicamentos e farmacovigilância

As respostas e explicações aparecem conforme você responde ao teste.

1. Qual é o objetivo principal da farmacovigilância?
   • Detectar, avaliar e prevenir danos causados por medicamentos após seu uso
   • Comercialização de novos medicamentos para médicos
   • Definir o preço de varejo dos medicamentos
   • Projetando embalagens de comprimidos
2. In the published n2c2 clinical NLP system, what information did the system extract from narrative notes?
   • Only patients’ handwritten signatures
   • Medication and adverse-event concepts and their relations
   • Only final regulatory decisions
   • Only medicine prices
3. O que a análise de desproporcionalidade detecta em bancos de dados de eventos adversos?
   • A diferença de preço entre medicamentos de marca e genéricos
   • Qual hospital enviou mais relatórios
   • Pares de eventos medicamentosos relatados com mais frequência do que o acaso estatístico poderia prever
   • Os prazos de validade dos medicamentos
4. What is VigiBase, according to Uppsala Monitoring Centre?
   • A database of randomized clinical-trial efficacy results only
   • A list of confirmed causal side effects for every medicine
   • A commercial catalogue of approved drug prices
   • The WHO global database of reported adverse events for medicines and vaccines
5. Para que é utilizado o MedDRA em pipelines de farmacovigilância?
   • Um vocabulário médico padronizado para codificar reações e condições
   • Uma marca de embalagens farmacêuticas
   • Um aplicativo de agendamento para médicos
   • Um tipo de scanner de ressonância magnética
6. Which sequence does UMC describe in its signal-management process?
   • Diagnosis, prescription, dispensing, billing and discharge
   • Detection, validation, prioritisation, assessment and communication
   • Data collection, automatic causality decision, recall and litigation
   • Model training, deployment, billing and marketing
7. How should a high disproportionality score in a spontaneous-report database be interpreted?
   • As a population incidence rate for all patients
   • As a confirmed causal adverse reaction
   • As a statistical signal for further assessment, not proof that the drug caused the event
   • As proof that no other factor contributed
8. Which four elements satisfy the minimum ICSR criteria in ICH E2D(R1)?
   • A confirmed causal link, a batch number, a prescriber signature, and a laboratory result
   • A product label, a randomized trial, a treatment response, and a safety committee vote
   • A hospital admission, a known dose, a genetic profile, and a published case report
   • An adverse event or other observation, a suspect or interacting product, an identifiable patient, and an identifiable reporter