Résumé
Isomorphic Labs mooy Alphabet/DeepMind biy soppi jéego yu am solo yi ci AlphaFold mu nekk motëru defar drog bu njëkk ci IA. Dafa am solo ndax li muy tekki du xam jëmmu protein yi kese waaye xam naka la molecule yi di lëkkaloo, te loolu mën na soppali ni ñuy gisee garab yi.
Isomorphic Labs Drug Discovery ñu ngi koy gëna xamee ci wàllu pexe, xeetu jëfandikoo, dogal ci platform, ak jàppante ci ecosystem.
Plongeur bu xóot
Isomorphic Labs ñu ngi ko sos ci 2021 te Demis Hassabis moo ko jiite, mu juddoo ci AlphaFold bu DeepMind, moo saafara jafe-jafe protein yu yàgg yi ci xam luy am ci 3D ci asid amino yi. Li Isomorphic bëgga wax mooy biologie mën nañu ko jàppee ni sistem buy jëfandikoo ay xibaar, suko defee IA mën na modele jaxasoo moleculaire yi ci anam wu jaar yoon ngir sos garab ci anam wu jaar yoon, du ci jéem ak njuumte. Ci 2024, ekip bi jàppale ci génne AlphaFold 3, biy wax luy waaja am ci protein yi boole ci ADN, ARN, ligand ak yeneen molecule - lu am solo ngir xam lëkkaloo drog. Isomorphic siñe na kontraa yu mëna am ay miliyaar ciy dolaar ak Eli Lilly ak Novartis, ci 2025 dajale $600 milioŋ ci xaalis bu bawoo ci biti ngir gëna suqali prograami drog yi ci biir klinik bi.
Gis-gis xarala
AlphaFold 3 moo wecci modulu jëmmal bu AlphaFold 2 ak benn generatër bu sukkandiko ci diffusion: dafay tàmbalee ci coordonnée atomik yu bari bruit ba noppi di leen dindi bruit ci anamu 3D bu wóor, lépp di aju ci joxe leeral yu xóot ci molecule yi ci laale. Loolu dafay may benn xeetu jëfandikoo protein yi, asid nucleique yi, ion yi ak drog yu ndaw yi ci benn complexe, di wax luy waaja am ci ni benn composé kandidaa di doxee ci poos biy lëkkale target bi - laaj bi gëna am solo ci jëmmal drog bi lalu ci structure.
xam drog ci laboratoire isomorphic
Isomorphic Labs mooy Alphabet/DeepMind biy soppi jéego yu am solo yi ci AlphaFold mu nekk motëru defar drog bu njëkk ci IA. Dafa am solo ndax li muy tekki du xam jëmmu protein yi kese waaye xam naka la molecule yi di lëkkaloo, te loolu mën na soppali ni ñuy gisee garab yi. Isomorphic Labs Drug Discovery ñu ngi koy gëna xamee ci wàllu pexe, xeetu jëfandikoo, dogal ci platform, ak jàppante ci ecosystem. Ngir tabax xam-xam bu xóot, jàppal Isomorphic Labs Drug Discovery ni xeetu liggéey, du benn man-man: leeral njariñ yi nga bëgg, leeral xalaat yi, ak tàqale li sistem bi mëna def ci anam wu wóor ak li ba leegi soxla àtteb kàngam.
Ci jëf, ekip yu am doole yiy jëfandikoo Isomorphic Labs Drug Discovery dañuy jàngat pexem jaaykat bi, wóorum kàrtu yoon wi, ak risku tëjug balaa ñuy jëfandikoo. Dañuy bind kritër yu leer ngir am ndam, natt leen ci done yu dëggu ak def liggéey, ba noppi ñu baamtu ci anamu ñàkka mëna seetlu, du ci benn yoon benchmark wins. Mooy barab bi xam-xam theorie bi di soppiku nekk kàttan buy yàgg ci produit yi, ci politik yi ak ci liggéey yi.
Kartu yoonu jaaykat yi ñooy wane man-man yi sa ekip mëna tabax ci kanam. Ci jamano jooju, annonce lansma yi mën nañu raw stabilite ci liggéeyu production dëgg. Xeetu jëf bi gëna dëgër mooy boole gaawaayu jàngat ak disipline nguur: doxal pilote, jàpp firnde, siiwal dogal yi, ak wéy di yeesal kaaraange gi ci anam wi ñuy doxalee, li jëfandikukat bi di xaar, ak sàrti sàrt yi di jëm kanam.
njeextalu pexe
Kartu yoonu jaaykat yi ñooy wane man-man yi sa ekip mëna tabax ci kanam.
Kartu yoonu jaaykat yi ñooy wane man-man yi sa ekip mëna tabax ci kanam. Ci jëfandikoo yu am kalite bu kawe, loolu dañu koy tekki ci sàrti liggéey yuñ mëna natt, ay peggu boroom, ak ay xew-xewu xoolaat yu bari suko defee ekip yi mëna yokk wóolu seen bopp ci barabu yokk lu jaxasoo.
Anamu jënd ak jaay ak tànneefi dugal dañu am njeexital ci njëg ak risk ci diir bu xawa yàgg.
Anamu jënd ak jaay ak tànneefi dugal dañu am njeexital ci njëg ak risk ci diir bu xawa yàgg. Ci jëfandikoo yu am kalite bu kawe, loolu dañu koy tekki ci sàrti liggéey yuñ mëna natt, ay peggu boroom, ak ay xew-xewu xoolaat yu bari suko defee ekip yi mëna yokk wóolu seen bopp ci barabu yokk lu jaxasoo.
Li liggéeyukaay bi di ñaax mooy tëral ni produit bi di doxee, kaaraange gi ak ubbeeku gi.
Li liggéeyukaay bi di ñaax mooy tëral ni produit bi di doxee, kaaraange gi ak ubbeeku gi. Ci jëfandikoo yu am kalite bu kawe, loolu dañu koy tekki ci sàrti liggéey yuñ mëna natt, ay peggu boroom, ak ay xew-xewu xoolaat yu bari suko defee ekip yi mëna yokk wóolu seen bopp ci barabu yokk lu jaxasoo.
Doxal ci àdduna dëgg
Jëfandikoo AlphaFold 3 ngir wane ni benn molecule bu ndaw di lëkkaloo ci biir poos bu protein biñ bëgga feebar laata ñuy jëfandikoo benn synthese ci labo.
Ñu ngi jëflante ak Eli Lilly ak Novartis ngir sos garab yu bees yu am molecule yu ndaw ngir feebar yu bari.
Xalaatal protein-ADN ak protein-ARN ngir jàngat mbir yu jumtukaayi yàgg yi mënu ñu woon wane.
Li gëna am solo ci composé chimik yi nga wara synthesize ak test, wàññi cycle wet-lab yu yàqu yi.
Modèlu jëfandikoo
Labs isomorphic gis drog ci jëf
Jëfandikoo AlphaFold 3 ngir wane ni benn molecule bu ndaw di lëkkaloo ci biir poos bu protein biñ bëgga feebar laata ñuy jëfandikoo benn synthese ci labo.
Jëfandikoo AlphaFold 3 ngir wane ni benn molecule bu ndaw di lëkkale ci biir poos bu protein biñ bëgga feebar balaa benn synthese lab. Ekip yi dañuy faral di am njariñ yu gëna baax suñu joxee ay threshold yu baax ci kanam, tëye yoon wi nit ñi di yokk ngir jafe-jafe yi, ba noppi topp njariñu produit yi ak njëgu njuumte yi ci diir bi.
Labs isomorphic gis drog ci jëf
Ñu ngi jëflante ak Eli Lilly ak Novartis ngir sos garab yu bees yu am molecule yu ndaw ngir feebar yu bari.
Partenariat ak Eli Lilly ak Novartis ngir sos ay garabi molecule yu ndaw ci wàllu feebar yu bari. Ekip yi dañuy faral di am njariñ yu gëna baax suñu joxe ay tegtal yu baax ci kanam, tëye yoonu escalation nit ngir jafe-jafe yi, ba noppi topp njariñu produit yi ak njëgu njuumte yi ci diir bu gàtt.
Labs isomorphic gis drog ci jëf
Xalaatal protein-ADN ak protein-ARN ngir jàngat mbir yu jumtukaayi yàgg yi mënu ñu woon wane.
Xalaatal protein-ADN ak protein-RNA complexes ngir jàngat ay mbir yu jumtukaay yu yàgg yi mënu ñu woon representé. Ekip yi dañuy faral di am njariñ yu gëna baax suñu leeralee kalite ci kanam, tëye yoonu escalation nit ngir jafe-jafe yi, ba noppi topp njariñu produit ak njëgu njuumte ci diir bu gàtt.
Labs isomorphic gis drog ci jëf
Li gëna am solo ci composé chimik yi nga wara synthesize ak test, wàññi cycle wet-lab yu yàqu yi.
Li gëna am solo ci composé chimik yi nga wara synthesize ak natt, wàññi waste wet-lab cycles Teams yi dañuy faral di am njariñ yu gëna baax suñu joxee thresholds yu baax ci kanam, tëye yoonu escalation nit ngir jafe-jafe yi, ba noppi topp njariñu produit ak njëgu njuumte ci diir bi.
Risk yi ak balustrade yi
Koom-koomu ubbite mën na raw stabilite ci def liggéeyu defar dëgg.
Njëg yi ci API wala coppite ci sàrt yi mën nañu dindi xalaat yi ci guddi gi.
Dependence ci benn jaaykat dafay yokk njëgu tëjug ak migraasioŋ.
Roadmap ngir samp gi
Saytu sa fournisseur yi nga jëfandikoo sa liggéey ak say done.
Saytu sa fournisseur yi nga jëfandikoo sa liggéey ak say done. Japp jéego bu nekk ni buntu firnde: sudee mattul kritër yi, noppali génne gi, tëj bërëb bi, ba noppi nga yaatal jëfandikoo gi.
Xoolaat mbir yu nëbbu, kaaraange ak sàrti yoon balaa ngay boole.
Xoolaat mbir yu nëbbu, kaaraange ak sàrti yoon balaa ngay boole. Japp jéego bu nekk ni buntu firnde: sudee mattul kritër yi, noppali génne gi, tëj bërëb bi, ba noppi nga yaatal jëfandikoo gi.
Fexe am palaŋu fallback ci model yi wala jaaykat yi.
Fexe am palaŋu fallback ci model yi wala jaaykat yi. Japp jéego bu nekk ni buntu firnde: sudee mattul kritër yi, noppali génne gi, tëj bërëb bi, ba noppi nga yaatal jëfandikoo gi.
Xool notu génne yi suko defee coppite yi ci kàrtu yoon du jaaxal ekip yi.
Xool notu génne yi suko defee coppite yi ci kàrtu yoon du jaaxal ekip yi. Japp jéego bu nekk ni buntu firnde: sudee mattul kritër yi, noppali génne gi, tëj bërëb bi, ba noppi nga yaatal jëfandikoo gi.