AI in Antibody and Protein Design Quiz

Answers and explanations appear as you take the quiz.

1. What did DeepMind's AlphaFold famously achieve?
   • Accurate protein structure prediction from sequence
   • Faster internet routing
   • Better weather forecasts
   • Cheaper solar panels
2. What does RFdiffusion do?
   • Plays chess
   • Generates novel protein backbones via diffusion
   • Translates languages
   • Compresses images
3. What is the role of ProteinMPNN in protein design?
   • It prints physical proteins
   • It measures temperature
   • It proposes amino-acid sequences compatible with a target backbone
   • It edits DNA in living patients
4. In antibodies, what part does AI often design to bind a target?
   • The cell membrane
   • The mitochondria
   • The ribosome
   • The CDR binding loops
5. Why is predicting how a designed protein chain folds so important?
   • Structure influences protein function, which still requires experimental testing
   • Color depends on it
   • It sets the cell's temperature
   • It determines blood type only
6. When an AI-designed protein is developed as a therapeutic biologic for human use in the United States, what additional step applies before marketing?
   • The applicable development and regulatory review, including a biologics license application when required
   • No review, because computational design establishes safety
   • Only a structure-prediction benchmark
   • Approval for every research protein before any laboratory study
7. What kind of structure does AlphaFold-Multimer aim to predict?
   • Only the DNA sequence of a single gene
   • The exact number of cells in a tissue
   • The arrangement of multiple interacting protein chains in a complex
   • The amino-acid sequence without any structure
8. What types of molecules can AlphaFold 3 model in addition to proteins?
   • Only additional protein chains
   • Only whole cells and tissues
   • Every chemical reaction rate in a living organism
   • DNA, RNA, and small-molecule ligands in biomolecular complexes